反应详情

To a 250 ml flask equipped with magnetic stirrer and reflux condenser was charged 10 g of 3-(4-chlorobenzoyl)-propionic acid, 250 ml. of absolute ethanol, and 2.5 ml of methyl hydrazine. The reaction was refluxed for 3 hours and cooled to yield a solid which was collected by vacuum filtration, washed with 50 ml of hexane, and air dried. Isolated 9.5 g of product as a white solid.

1. customTo a 250 ml flask equipped with magnetic stirrer
2. temperaturereflux condenser
3. temperatureThe reaction was refluxed for 3 hours
4. temperaturecooled
5. customto yield a solid which
6. filtrationwas collected by vacuum filtration
7. washwashed with 50 ml of hexane, and air
8. customdried