化工社化工社 化学情報印刷レポート · 研究参考用
1,1-Diphenylbutane-1,4-diol → 4,4-Diphenylbutan-1-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,1-Diphenylbutane-1,4-diol | HCID 96679 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4,4-Diphenylbutan-1-ol | HCID 92519 | 91% |
反応手順
1,1-Diphenyl-1,4-butanediol (26.62 g, 0.110 mol) was dissolved in MeOH and shaken with 20% Pd/C (1.50 g) on a Parr apparatus under an H2 atmosphere (50 psi) for 17 hours. The MeOH was removed in vacuo, and the residue chromatographed on silica gel eluting with 35% EtOAc/Hexanes gave 22.53 g (91%) of desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05932573 |
| 出典データセット | uspto-grants-1999_08 |
| ORD ID | ord-6a3f573298264b5b9862ccb9e3abc4a4 |
| 出典メモ | uspto-grants-1999_08 |