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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15842Generated: October 25, 2026

4-Methylphthalic anhydride → 5-methyl-2-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1H-isoindole-1,3(2H)-dione

https://huagongshe.com/reaction/15842

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methylphthalic anhydrideHCID 88069—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
Product5-methyl-2-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1H-isoindole-1,3(2H)-dioneHCID 57444327—

Reaction Steps

Prepared from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 5-methyl-2-benzofuran-1,3-dione according to Method I.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732600B2
Source datasetuspto-grants-2010_06
ORD IDord-be96a93abf754fa9b79d7717f41e346c
Source noteuspto-grants-2010_06