HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-chloromethyl-2-[(E)-styryl]thiazole → 5-[3-[3-methoxy-4-[2-[(E)-styryl]-4-thiazolylmethoxy]-phenyl]propyl]-2,4-oxazolidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-chloromethyl-2-[(E)-styryl]thiazole | HCID 22009735 | — |
| Reactant | 5-[3-(4-Hydroxy-3-methoxyphenyl)propyl]-2,4-oxazolidinedione | HCID 69830471 | — |
| Product | 5-[3-[3-methoxy-4-[2-[(E)-styryl]-4-thiazolylmethoxy]-phenyl]propyl]-2,4-oxazolidinedione | HCID 69830939 | — |
Reaction Steps
In substantially the same manner as in Working Example 9, 5-[3-(4-hydroxy-3-methoxyphenyl)propyl]-2,4-oxazolidinedione was allowed to react with 4-chloromethyl-2-[(E)-styryl]thiazole to yield 5-[3-[3-methoxy-4-[2-[(E)-styryl]-4-thiazolylmethoxy]-phenyl]propyl]-2,4-oxazolidinedione. The product was recrystallized from chloroform-methanol to give colorless prisms, m.p.202-203° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05932601 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-e0644545b89c41b5b56956141ad7697b |
| Source note | uspto-grants-1999_08 |