2,4-Oxazolidinedione → HCID 69831316, compound

HRID 1584302Notes

Reaction equation

[CH:1]([O:4][C:5]1[CH:6]=[C:7]([CH:12]=[CH:13][C:14]=1[O:15][CH2:16][C:17]1[N:18]=[C:19]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[O:20][C:21]=1[CH3:22])[CH:8]=[CH:9][CH:10]=O)([CH3:3])[CH3:2].[O:29]1[CH2:33][C:32](=[O:34])[NH:31][C:30]1=[O:35]>>[CH:1]([O:4][C:5]1[CH:6]=[C:7]([CH2:8][CH2:9][CH2:10][CH:33]2[O:29][C:30](=[O:35])[NH:31][C:32]2=[O:34])[CH:12]=[CH:13][C:14]=1[O:15][CH2:16][C:17]1[N:18]=[C:19]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[O:20][C:21]=1[CH3:22])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 973892,4-Oxazolidinedione

HCID 54055328HCID 54055328, compound

Product 1

HCID 69831316HCID 69831316, compound

Procedure

In substantially the same manner as in Working Example 11, 3-isopropoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)cinnamaldehyde was condensed with 2,4-oxazolidinedione. The condensate was subjected to catalytic hydrogenation to yield 5-[3-[3-isopropoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]propyl]-2,4-oxazolidinedione, which was recrystallized from ethyl acetate-hexane to give colorless needles, m.p.120-121° C.

Sources & evidence

ORD record: ord-43bbb22d8f214f109816a1cd36cbcb97
Source dataset: uspto-grants-1999_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05932601

Reaction notes

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