HCID 13282937, compound → HCID 69830975, compound

HRID 1584320Notes

Reaction equation

HRID 1584320 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH:12]2[O:16][C:15](=[O:17])[NH:14][C:13]2=[O:18])=[CH:4][C:3]=1[O:19][CH3:20].Cl[CH2:22][C:23]1[N:24]=[C:25](/[CH:29]=[CH:30]/[C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[O:26][C:27]=1C>>[CH3:20][O:19][C:3]1[CH:4]=[C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH:12]2[O:16][C:15](=[O:17])[NH:14][C:13]2=[O:18])[CH:6]=[CH:7][C:2]=1[O:1][CH2:22][C:23]1[N:24]=[C:25](/[CH:29]=[CH:30]/[C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[O:26][CH:27]=1

Participants

3

Reactant 2

HCID 13282937HCID 13282937, compoundHCID 69830919HCID 69830919, compound

Product 1

HCID 69830975HCID 69830975, compound

Procedure

In substantially the same manner as in Working Example 9, 5-[4-(4-hydroxy-3-methoxyphenyl)butyl]-2,4-oxazolidinedione was reacted with 4-chloromethyl-5-methyl-2-[(E)-styryl]oxazole to obtain 5-[4-[3-methoxy-4-[2-[(E)-styryl]-4-oxazolylmethoxy]phenyl]butyl]-2,4-oxazolidinedione, which was recrystallized from ethyl acetate-hexane to give colorless prisms, m.p.171-172° C.

Sources & evidence

ORD record
ord-7c4734607e1b408da6e0f2883159d8c1
Source dataset
uspto-grants-1999_08
Patent number
US05932601

Reaction notes

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