Potassium cyanate → HCID 69830649, compound

HRID 1584322Notes

Reaction equation

[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH:17]([OH:23])[C:18]([O:20]CC)=O)=[CH:11][C:10]=1[O:24][CH2:25][CH3:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O-:27][C:28]#[N:29].[K+]>>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH:17]2[O:23][C:28](=[O:27])[NH:29][C:18]2=[O:20])=[CH:11][C:10]=1[O:24][CH2:25][CH3:26])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 11378442Potassium cyanate

HCID 21224401HCID 21224401, compound

Product 1

HCID 69830649HCID 69830649, compound

Procedure

In substantially the same manner as in Working Example 34, ethyl 4-(4-benzyloxy-3-ethoxyphenyl)-2-hydroxybutanoate was reacted with potassium cyanate (KCNO) to obtain 5-[2-(4-benzyloxy-3-ethoxyphenyl)ethyl]-2,4-oxazolidinedione, which was recrystallized from ethyl acetate-hexane to give colorless prisms, m.p.143-144° C.

Sources & evidence

ORD record: ord-411d5f945e8f4419923880451bd39a59
Source dataset: uspto-grants-1999_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05932601

Reaction notes

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