HCID 13282937, compound → HCID 69830524, compound

HRID 1584324Notes

Reaction equation

HRID 1584324 reaction equation
[OH:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([CH2:10][CH2:11][CH2:12][CH:13]2[O:17][C:16](=[O:18])[NH:15][C:14]2=[O:19])=[CH:4][C:3]=1[O:20][CH3:21].Cl[CH2:23][C:24]1[N:25]=[C:26](/[CH:30]=[CH:31]/[C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[O:27][C:28]=1C>>[CH3:9][O:8][C:7]1[CH:6]=[C:5]([CH2:10][CH2:11][CH2:12][CH:13]2[O:17][C:16](=[O:18])[NH:15][C:14]2=[O:19])[CH:4]=[C:3]([O:20][CH3:21])[C:2]=1[O:1][CH2:23][C:24]1[N:25]=[C:26](/[CH:30]=[CH:31]/[C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[O:27][CH:28]=1

Participants

3

Reactant 2

HCID 13282937HCID 13282937, compoundHCID 69830662HCID 69830662, compound

Product 1

HCID 69830524HCID 69830524, compound

Procedure

In substantially the same manner as in Working Example 9, 5-[3-(4-hydroxy-3,5-dimethoxyphenyl)propyl]-2,4-oxazolidinedione was reacted with 4-chloromethyl-5-methyl-2-[(E)-styryl]oxazole to obtain 5-[3-[3,5-dimethoxy-4-[2-[(E)-styryl]-4-oxazolylmethoxy]phenyl]propyl]-2,4-oxazolidinedione, which was recrystallized from ethyl acetate-hexane to give colorless prisms, m.p.94-95° C.

Sources & evidence

ORD record
ord-3e4588175b664b24935c14f0fd219527
Source dataset
uspto-grants-1999_08
Patent number
US05932601

Reaction notes

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