HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisobutylaluminumhydride → (E,E)-5-[3-methoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadien-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | methyl (E,E)-5-[3-methoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadienoate | HCID 131721330 | — |
| Product | (E,E)-5-[3-methoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadien-1-ol | HCID 21224491 | — |
Reaction Steps
In substantially the same manner as in Reference Example 24, methyl (E,E)-5-[3-methoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadienoate was subjected to reduction with diisobutylaluminum hydride to yield (E,E)-5-[3-methoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadien-1-ol, which was recrystallized from ethyl acetate to give colorless needles, m.p.149-151° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05932601 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-272b07e0465d4a38994f3c4d69c4453c |
| Source note | uspto-grants-1999_08 |