反应详情

Activated manganese dioxide (28.0 g) was added to a solution of (E)-3-[3-methoxy-4-(2-phenyl-4-oxazolyl-methoxy)phenyl]-2-propen-1-ol (13.6 g) in chloroform (250 ml). The mixture was stirred for 8 hours at room temperature, which was subjected to filtration through a celite layer. The filtrate was concentrated to yield 3-methoxy-4-(2-phenyl-4-oxazolylmethoxy)cinnamaldehyde (11.8 g, 88%), which was recrystallized from ethyl acetate-hexane to give colorless needles, m.p.144-145° C.

1. filtrationwhich was subjected to filtration through a celite layer
2. concentrationThe filtrate was concentrated