HCID 21224432, compound → HCID 54247056, compound

HRID 1584349Notes

Reaction equation

HRID 1584349 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](/[CH:9]=[CH:10]/[CH2:11][OH:12])=[CH:5][C:4]=1[O:13][CH2:14][C:15]1[N:16]=[C:17]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[O:18][C:19]=1[CH3:20]>[O-2].[O-2].[Mn+4]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][CH:11]=[O:12])=[CH:5][C:4]=1[O:13][CH2:14][C:15]1[N:16]=[C:17]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[O:18][C:19]=1[CH3:20]

Participants

3

Reactant 1

HCID 21224432HCID 21224432, compound

Product 1

HCID 54247056HCID 54247056, compound

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

In substantially the same manner as in Reference Example 35, (E)-3-[4-methoxy-3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-propen-1-ol was subjected to oxidation with activated manganese dioxide to yield 4-methoxy-3-(5-methyl-2-phenyl-4-oxazolylmethoxy)cinnam aldehyde, which was recrystallized from ethyl acetate-ether to give pale yellow needles, m.p.136-137° C.

Sources & evidence

ORD record
ord-eb51bb9f82c44b18b74478dbc2ec1f0b
Source dataset
uspto-grants-1999_08
Patent number
US05932601

Reaction notes

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