Diisobutylaluminumhydride → HCID 21224447, compound

HRID 1584365Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:13]=[CH:14][C:15]=1[O:16][CH:17]([C:19]1[N:20]=[C:21]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[O:22][C:23]=1[CH3:24])[CH3:18])[CH:6]=[CH:7][C:8](OCC)=[O:9].[H-].C([Al+]CC(C)C)C(C)C>>[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:6]=[CH:7]/[CH2:8][OH:9])[CH:13]=[CH:14][C:15]=1[O:16][CH:17]([C:19]1[N:20]=[C:21]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[O:22][C:23]=1[CH3:24])[CH3:18]

Participants

Reactant 2

HCID 21225700Diisobutylaluminumhydride

HCID 53966559HCID 53966559, compound

Product 1

HCID 21224447HCID 21224447, compound

Procedure

In substantially the same manner as in Reference Example 24, ethyl 3-methoxy-4-[1-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]cinnamate was subjected to reduction reaction with diisobutylaluminum hydride to yield (E)-3-[3-methoxy-4-[1-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]-2-propen-1-ol.

Sources & evidence

ORD record: ord-f673355bf7254461a5b71b020d5e23c2
Source dataset: uspto-grants-1999_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05932601

Reaction notes

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