HCID 21224447, compound → HCID 57040319, compound

HRID 1584366Notes

Reaction equation

HRID 1584366 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:24]=[CH:25]/[CH2:26][OH:27])[CH:6]=[CH:7][C:8]=1[O:9][CH:10]([C:12]1[N:13]=[C:14]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[O:15][C:16]=1[CH3:17])[CH3:11]>[O-2].[O-2].[Mn+4]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][C:8]=1[O:9][CH:10]([C:12]1[N:13]=[C:14]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[O:15][C:16]=1[CH3:17])[CH3:11])[CH:24]=[CH:25][CH:26]=[O:27]

Participants

3

Reactant 1

HCID 21224447HCID 21224447, compound

Product 1

HCID 57040319HCID 57040319, compound

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

In substantially the same manner as in Reference Example 35, (E)-3-[3-methoxy-4-[1-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]-2-propen-1-ol was subjcted to oxidation reaction with activated manganese dioxide to yield 3-methoxy-4-[1-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]cinnamaldehyde, which was recrystallized from acetone-isopropyl ether to give colorless needles, m.p.152-153° C.

Sources & evidence

ORD record
ord-a9b33f12736547a29f1ed83670572cf8
Source dataset
uspto-grants-1999_08
Patent number
US05932601

Reaction notes

Loading…