HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(tert-butoxy)-2-[1-(4-phenoxyphenylthio)cyclopent-1-yl]-acetamide → N-hydroxy-2-[1-(4-phenoxyphenylthio)-cyclopent-1-yl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(tert-butoxy)-2-[1-(4-phenoxyphenylthio)cyclopent-1-yl]-acetamide | HCID 21224113 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | N-hydroxy-2-[1-(4-phenoxyphenylthio)-cyclopent-1-yl]-acetamide | HCID 21224318 | — |
Reaction Steps
The N-tert-butoxy-2-[1-(4-phenoxyphenylthio)-cyclopent-1-yl]-acetamide was dissolved in trifluoroacetic acid (6 ml) and allowed to stand for 24 hours. The acid was evaporated off under reduced pressure and the product purified by preparative TLC, eluting with 6.5% methanol/methylene chloride gave N-hydroxy-2-[1-(4-phenoxyphenylthio)-cyclopent-1-yl]-acetamide (100 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05932595 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-ff650d42c7dc4b5b89dc19df337cac31 |
| Source note | uspto-grants-1999_08 |