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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1584543Generated: November 1, 2026

Methanesulfonyl chloride → 9-(2-Methanesulfonyloxyethyl)-2,4-di-1-pyrrolidinyl-9H-pyrimido[4,5-b]indole

https://huagongshe.com/reaction/1584543

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant2-[2,4-Di(pyrrolidin-1-yl)-9H-pyrimido[4,5-b]indol-9-yl]ethan-1-olHCID 15521616—
Product9-(2-Methanesulfonyloxyethyl)-2,4-di-1-pyrrolidinyl-9H-pyrimido[4,5-b]indoleHCID 53732408—

Reaction Steps

9-[2-(Hydroxy)ethyl]-2,4-di-1-pyrrolidinyl-9H-pyrimido[4,5-b]indole (I, J. Med. Chem., 38, 4161-3 (1995) is reacted with methanesulfonyl chloride by means known to those skilled in the art to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05932728
Source datasetuspto-grants-1999_08
ORD IDord-ee786996b7224d118975b77baf8e2c14
Source noteuspto-grants-1999_08