HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isonicotinoyl chloride hydrochloride → N-(N,N-Dipropyl-1,2,3,4-tetrahydro-2-aminodibenzofur-8-yl)isonicotinamide dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isonicotinoyl chloride hydrochloride | HCID 12262826 | — |
| Reactant | 8-Amino-1,2,3,4-tetrahydro-2-dipropylaminodibenzofuran | HCID 21221545 | — |
| Product | N-(N,N-Dipropyl-1,2,3,4-tetrahydro-2-aminodibenzofur-8-yl)isonicotinamide dihydrochloride | HCID 21221711 | 81% |
Reaction Steps
Beginning with 0.072 gm (0.20 mMol) 8-amino-1,2,3,4-tetrahydro-2-dipropylaminodibenzofuran and 0.054 gm (0.30 mMol) isonicotinoyl chloride hydrochloride, 0.075 gm (81%) of the title compound were recovered as a yellow solid by the procedure described in Example 17.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05932739 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-b443b3c95eae414d9bd8d626e9b65bd4 |
| Source note | uspto-grants-1999_08 |