Ethyl 4-amino-1-piperidinecarboxylate → 4-[6-Amino-5-(5-fluoro-2-methoxy-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid ethyl ester

HRID 158476Notes

Reaction equation

HRID 158476 reaction equation
[CH2:20]([CH3:21])[O:22][C:23](=[O:24])[N:25]1[CH2:26][CH2:27][CH:28]([NH2:31])[CH2:29][CH2:30]1.[NH2:1][c:2]1[n:3][c:4]([Cl:19])[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:17][CH3:18])[cH:12][cH:13][c:14]([F:16])[cH:15]1>>[NH2:1][c:2]1[n:3][c:4]([NH:31][CH:28]2[CH2:27][CH2:26][N:25]([C:23]([O:22][CH2:20][CH3:21])=[O:24])[CH2:30][CH2:29]2)[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:17][CH3:18])[cH:12][cH:13][c:14]([F:16])[cH:15]1

Participants

3

Reactant 2

HCID 100867Ethyl 4-amino-1-piperidinecarboxylateHCID 58590829(2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-phenyl)-methanone

Product 1

HCID 116688374-[6-Amino-5-(5-fluoro-2-methoxy-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-4dc6be6f451642d080fccb63ebd8dd14
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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