反应详情

[5-(5-Methyl-tetrazol-1-yl)-benzofuran-7-yl]-methanol (124 mg,) and manganese (IV) oxide (140 mg) in 1,4-dioxan (5 ml) was heated at reflux for 18 h. A further portion of manganese (IV) oxide (210 mg) was added and heating continued for 2 h. The reaction mixture was filtered through a plug of Hyflo, the pad was washed with chloroform (20 ml) and the filtrate was evaporated in vacuo to give the title compound as a white powder (77 mg).

1. temperatureat reflux for 18 h
2. temperatureheating
3. filtrationThe reaction mixture was filtered through a plug of Hyflo
4. washthe pad was washed with chloroform (20 ml)
5. customthe filtrate was evaporated in vacuo