Furan-3-boronic acid → HCID 70109202, compound

HRID 1584794Notes

Reaction equation

HRID 1584794 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([N:14]([CH2:22][C:23]2[C:31]3[O:30][CH:29]=[CH:28][C:27]=3[CH:26]=[C:25](Br)[CH:24]=2)[C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[C@@H:9]1[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[O:39]1[CH:43]=[CH:42][C:41](B(O)O)=[CH:40]1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([N:14]([CH2:22][C:23]2[C:31]3[O:30][CH:29]=[CH:28][C:27]=3[CH:26]=[C:25]([C:41]3[CH:42]=[CH:43][O:39][CH:40]=3)[CH:24]=2)[C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[C@@H:9]1[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 2734358Furan-3-boronic acidHCID 70107045HCID 70107045, compound

Product 1

HCID 70109202HCID 70109202, compound

Procedure

From cis-3-[(5-bromobenzofuran-7-ylmethyl)tert-butoxycarbonyl-amino]-2-phenyl-piperidine-1-carboxylic acid tert-butyl ester (473 mg) and 3-furanboronic acid (102 mg).

Sources & evidence

ORD record
ord-55a76509eed14068bf883fdc188b3912
Source dataset
uspto-grants-1999_08
Patent number
US05935972

Reaction notes

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