Ethanol → 1-(2,6-Dichloro-3-pyridylmethyl)amino-1-methylamino-2-nitroethylene

HRID 1585033Notes

Reaction equation

HRID 1585033 reaction equation
[Cl:1][C:2]1[C:7]([CH2:8][NH2:9])=[CH:6][CH:5]=[C:4]([Cl:10])[N:3]=1.C[C:12]([NH2:19])(SC)[CH2:13][N+:14]([O-:16])=[O:15].[CH3:20]CO>>[Cl:1][C:2]1[C:7]([CH2:8][NH:9][C:12]([NH:19][CH3:20])=[CH:13][N+:14]([O-:16])=[O:15])=[CH:6][CH:5]=[C:4]([Cl:10])[N:3]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 15477284(2,6-Dichloropyridin-3-YL)methanamineHCID 224505461-Methyl-amino-1-methylthio-2-nitroethane

Product 1

HCID 598966091-(2,6-Dichloro-3-pyridylmethyl)amino-1-methylamino-2-nitroethylene

Procedure

A mixture of 1.2 g (0.007 mole) of (2,6-dichloro-3-pyridylmethyl)amine and 1 g (0.007 mole) of 1-methyl- amino-1-methylthio-2-nitroethane was refluxed in 50 ml of EtOH for 6 hours. After cooling, the reaction mixture was concentrated and the resulting crystals were collected by filtration, washed with CH2Cl2 and a small amount of EtOH in that order and dried. The procedure gave 0.53 g of the title compound as a white powder.

Workup

  1. temperatureAfter cooling
  2. concentrationthe reaction mixture was concentrated
  3. filtrationthe resulting crystals were collected by filtration
  4. washwashed with CH2Cl2
  5. dry with materiala small amount of EtOH in that order and dried

Sources & evidence

ORD record
ord-2ad2527839504aa181ca23e4c26888bc
Source dataset
uspto-grants-1999_08
Patent number
US05935981

Reaction notes

Loading…