HCID 18391175, compound → HCID 131721332, compound

Participants

Reaction Steps

Silver oxide (0.23 g, 0.992 mmol) and 2-(N-BOC,N-methylamino)-4-nitrophenol (3) were added to a solution of methyl 2,3,4-tri-O-acetyl-a-D-glucuronate bromide (4) (126 mg, 0.317 mmol) in acetonitrile (5 ml). The reaction mixture was stirred at room temperature for 1 hour, filtered through Celite and concentrated in vacuo. The product was chromatographed on silica gel (eluent dichloromethane/methanol 97.5/2.5). Yield 165 mg (89%).

Provenance & Evidence