4-Hydroxy-3,5-bis(isopropyl)benzaldehyde → (E)-2-(Benzylaminosulfonyl)-3-(3,5-diisopropyl-4-hydroxyphenyl)acrylonitrile

HRID 1585109Notes

Reaction equation

HRID 1585109 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:13]([CH3:15])[CH3:14])[C:11]=1[OH:12])[CH:7]=O)([CH3:3])[CH3:2].[CH2:16]([NH:23][S:24]([CH2:27][C:28]#[N:29])(=[O:26])=[O:25])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([NH:23][S:24](/[C:27](=[CH:7]/[C:6]1[CH:5]=[C:4]([CH:1]([CH3:3])[CH3:2])[C:11]([OH:12])=[C:10]([CH:13]([CH3:15])[CH3:14])[CH:9]=1)/[C:28]#[N:29])(=[O:26])=[O:25])[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 827124-Hydroxy-3,5-bis(isopropyl)benzaldehydeHCID 15410493HCID 15410493, compound

Product 1

HCID 18185617(E)-2-(Benzylaminosulfonyl)-3-(3,5-diisopropyl-4-hydroxyphenyl)acrylonitrile

Procedure

The titled compound was prepared with 3,5-diisopropyl-4-hydroxybenzaldehyde and N-benzyl cyanomethylsulfonamide under the similar conditions as described for EXAMPLE 12 (part B).

Sources & evidence

ORD record
ord-ccc1ae40067e44dabd16a7b55b54f879
Source dataset
uspto-grants-1999_08
Patent number
US05935993

Reaction notes

Loading…