HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isonicotinoyl chloride hydrochloride → N-(N,N-Diethyl-1,2,3,4-tetrahydro-2-aminodibenzofur-8-yl)isonicotinamide dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isonicotinoyl chloride hydrochloride | HCID 12262826 | — |
| Reactant | 8-Amino-1,2,3,4-tetrahydro-2-diethylaminodibenzofuran | HCID 21221558 | — |
| Product | N-(N,N-Diethyl-1,2,3,4-tetrahydro-2-aminodibenzofur-8-yl)isonicotinamide dihydrochloride | HCID 21221697 | 52% |
Reaction Steps
Beginning with 0.100 gm (0.30 mMol) 8-amino-1,2,3,4-tetrahydro-2-diethylaminodibenzofuran and 0.059 gm (0.33 mMol) isonicotinoyl chloride hydrochloride, 0.068 gm (52%) of the title compound were recovered as a yellow solid by the procedure described in Example 17.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05935992 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-61c8a2e8d528442e8ac111d0e5fffa95 |
| Source note | uspto-grants-1999_08 |