HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 22874290, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 70149533 | HCID 70149533 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 22874290 | HCID 22874290 | — |
Reaction Steps
In analogy with Example 44d), 1.315 g of 5(S)-[1(S)-(Boc-amino)-2-phenylethyl]-3(R)-[(3-methoxyphenyl)methyl]dihydrofuran-2-(3H)-one in 49.9 ml of dimethoxyethane and 25.16 ml of water are hydrolysed with 12.36 ml of a 1M lithium hydroxide solution to give the title compound, which is directly subjected to further processing. TLC Rf (C)=0.09. FAB-MS (M+H)+ =444.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05935976 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-4828c8a5fac446adb9c74796bcacb526 |
| Source note | uspto-grants-1999_08 |