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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1585445Generated: October 26, 2026

4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)- → Apomorphine

https://huagongshe.com/reaction/1585445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)-HCID 9410—
ReactantGlutathioneHCID 124886—
ReactantHCID 178504327HCID 178504327—
ProductApomorphineHCID 6005—

Reaction Steps

An apomorphine transdermal patch formulation was prepared by adding 1 milliliter of a ethanolic solution of 20 mg/ml apomorphine HCl and 2.6 mg/ml glutathione to 2 g of polydimethylsiloxane 200 and mixing until the mixture congealed.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05939094
Source datasetuspto-grants-1999_08
ORD IDord-4ee8761c431847b4bc4142ac07a1b402
Source noteuspto-grants-1999_08