Methanol → HCID 54376030, compound

Participants

Reaction Steps

10 g (0.044 mol) of methyl 3-methoxy-2-methyl-4-methylthiobenzoate was dissloved in 90 ml of methylene chloride, and the solution was added dropwise to 90 ml of methylene chloride containing 8.4 ml (0.088 mol) of boron tribromide at 5 to 10° C. After stirring at room temperature for 4 hours, 50 ml of methanol was added dropwise under ice cooling, and the solution was then washed with water and next a saturated sodium chloride solution. After drying over anhydrous magnesium sulfate, the solvent was distilled off under reduced pressure to obtain 9.2 g of methyl 3-hydroxy-2-methyl-4-methylthiobenzoate. Yield=98%.

Provenance & Evidence