Benzyl 2-hydroxyacetate → Benzyl 2-(((trifluoromethyl)sulfonyl)oxy)acetate

HRID 1585498Notes

Reaction equation

HRID 1585498 reaction equation
[S:1]([O:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])([C:4]([F:7])([F:6])[F:5])(=[O:3])=[O:2].OCC(OC[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=O>>[S:1]([O:8][CH2:9][C:10]([O:12][CH2:13][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:11])([C:4]([F:6])([F:7])[F:5])(=[O:3])=[O:2]

Participants

3

Reactant 2

HCID 561337Benzyl 2-hydroxyacetateHCID 112297732-(((Trifluoromethyl)sulfonyl)oxy)acetic acid methyl ester

Product 1

HCID 10902591Benzyl 2-(((trifluoromethyl)sulfonyl)oxy)acetate

Procedure

Prepared in the same way as described for TfO-CH2COOMe starting with HO-CH2COOBn

Workup

  1. customPrepared in the same way

Sources & evidence

ORD record
ord-d295b81fa1084aeebf3105a23aadfe8c
Source dataset
uspto-grants-1999_08
Patent number
US05939392

Reaction notes

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