Glycolic Acid → HCID 18506466, compound

Participants

Reaction Steps

To 215 mg (2.82 mmol) glycolic acid in 12.8 ml CH3CN was added 719 mg (3.39 mmol) 1-hexyl iodide and 429 mg (2.82 mmol) DBU. After stirring over night and reflux for 4 h, the solvent was evaporated, ethylacetat and 1 M KHSO4 was added and the phases were separated. The organic layer was washed with brine, dried (MgSO4), filtered and evaporated in vacuo to give 333 mg (74%) of the product.

Provenance & Evidence