Morpholine → HCID 15907531, compound

HRID 1585550Notes

Reaction equation

HRID 1585550 reaction equation
[CH2:1]([N:3]1[C:11]2[N:10]=[C:9]([CH2:12][CH3:13])[NH:8][C:7]=2[C:6](=S)[NH:5][C:4]1=[S:15])[CH3:2].[NH:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>CC(C)=O>[CH2:1]([N:3]1[C:11]2[N:10]=[C:9]([CH2:12][CH3:13])[NH:8][C:7]=2[C:6]([N:16]2[CH2:21][CH2:20][O:19][CH2:18][CH2:17]2)=[N:5][C:4]1=[S:15])[CH3:2]

Participants

4

Reactant 2

HCID 8083MorpholineHCID 15907530HCID 15907530, compound

Product 1

HCID 15907531HCID 15907531, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The product of stage (i) (14.42 g) was refluxed in 78.4 ml (900 mmoles) of morpholine for 30 hours. After cooling to room temperature the reaction product was suspended in 100 ml of acetone and the title product (16.49 g) collected and washed.

Workup

  1. customthe title product (16.49 g) collected
  2. washwashed

Sources & evidence

ORD record
ord-ef9483a314fe4a5dbad2a0b96d46db0b
Source dataset
uspto-grants-1999_08
Patent number
US05939422

Reaction notes

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