1-Iodohexane → HCID 86584056, compound

HRID 1585643Notes

Reaction equation

[C:1]([C:3]1[CH:23]=[CH:22][C:6]([C:7]([C:9]2[N:13]([CH3:14])[C:12]([CH2:15][C:16]([O:18]CC)=[O:17])=[CH:11][C:10]=2[CH3:21])=[O:8])=[CH:5][CH:4]=1)#[N:2].C(I)CCCCC>>[CH2:15]([C:12]1[N:13]([CH3:14])[C:9]([C:7](=[O:8])[C:6]2[CH:22]=[CH:23][C:3]([C:1]#[N:2])=[CH:4][CH:5]=2)=[C:10]([CH3:21])[CH:11]=1)[CH3:16].[CH2:12]([CH2:15][C:16]([O-:18])=[O:17])[CH2:11][CH2:10][CH2:9][CH2:7][CH3:6]

Participants

Reactant 2

HCID 125271-Iodohexane

HCID 18424306HCID 18424306, compound

Product 1

HCID 86584056HCID 86584056, compound

Procedure

The alkylation procedure of Example 77A is performed upon ethyl 5-(p-cyanobenzoyl)-1,4-dimethylpyrrole-2-acetate (from Example 93), using an equivalent quantity of n-hexyl iodide instead of methyl iodide used in Example 77A to yield ethyl 5-(p-cyanobenzoyl)-1,4-dimethylpyrrole-2-(α-n-hexyl)-acetate.

Sources & evidence

ORD record: ord-27373b633883446292910e58cd085fbf
Source dataset: uspto-grants-1999_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05939417

Reaction notes

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