HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Ethanediol → 2-(3-Chloropropyl)-2-phenyl-1,3-dioxolane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Ethanediol | HCID 151211 | — |
| Reactant | 4-Chlorobutyrophenone | HCID 253533 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-(3-Chloropropyl)-2-phenyl-1,3-dioxolane | HCID 12866338 | 111.6% |
Reaction Steps
4-Chlorobutyrophenone (15.18 g, 0.083 moles), ethanediol (6.80 g, 0.110 moles) and p-toluene sulphonic acid (0.20 g) were heated in toluene at reflux and water was removed from the reaction using a Dean and Stark apparatus. After 17 hours the solvent was removed by distillation in vacuo to leave crude 2-phenyl-2-(3-chloropropyl)-1,3-dioxolane (21 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05939447 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-3d2fcc7e27644a48bc71b43e6a7389cd |
| Source note | uspto-grants-1999_08 |