(4-chloro-2-Methylphenoxy)acetic acid → Acetic acid, 2-(4-chloro-2-methylphenoxy)-, sodium salt (1:1)

HRID 1585828Notes

Reaction equation

HRID 1585828 reaction equation
[CH3:1][C:2]1[CH:12]=[C:11]([Cl:13])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([OH:8])=[O:7].[OH-].[Na+:15]>CO>[CH3:1][C:2]1[CH:12]=[C:11]([Cl:13])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([O-:8])=[O:7].[Na+:15]

Participants

4

Reactant 2

HCID 7204(4-chloro-2-Methylphenoxy)acetic acid2×HCID 14798Sodium Hydroxide

Product 1

HCID 2724048Acetic acid, 2-(4-chloro-2-methylphenoxy)-, sodium salt (1:1)Yield 99.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

20 parts (0.1 mol) of 2-methyl-4-chlorophenoxyacetic acid (MCPA) (94.7%) are melted at 130° C. and reacted with 45 parts (0.1 mol, based on 100%) of 8.9% strength sodium hydroxide solution with simultaneous removal of methanol by distillation. After complete removal of methanol by distillation, 23.5 parts of MCPA-sodium of m.p. 227-230° C. are obtained, containing 80.8% MCPA, which corresponds to a yield of 99.7%.

Workup

  1. customAfter complete removal of methanol
  2. distillationby distillation, 23.5 parts of MCPA-sodium of m.p. 227-230° C.
  3. customare obtained

Sources & evidence

ORD record
ord-eee72ed5d6ee4f83924ed2822073b11b
Source dataset
uspto-grants-1999_08
Patent number
US05939584

Reaction notes

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