HCID 56981792, compound → HCID 21219597, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C@H:14]([OH:29])[CH2:15][C@H:16]([CH2:20][CH2:21][CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[C:17]([OH:19])=[O:18])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.ClC1C=CC(C2C=CC([C@@H](O)C[C@H](CCCC3C=CC=CC=3)C(O)=O)=CC=2)=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]([OH:29])[CH2:15][CH:16]([CH2:20][CH2:21][CH2:22][C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)[C:17]([OH:19])=[O:18])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1Participants
3
Procedure
the more active of the compounds [2S, 4R]-4-[4-(4-chlorophenyl)phenyl]-4-hydroxy-2-(3-phenylpropyl)-butanoic acid and [2S, 4S]-4-[4-(4-chlorophenyl)phenyl]-4-hydroxy-2-(3-phenylpropyl)-butanoic acid;
Sources & evidence
- ORD record
- ord-7c094c37b46e49c1ad9f20219fe07b32
- Source dataset
- uspto-grants-1999_08
- Patent number
- US05939583
Reaction notes
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