Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 3-Chloro-6-[(prop-2-en-1-yl)sulfanyl]pyridazine | HCID 21217667 | — |
| Product | HCID 21217669 | HCID 21217669 | — |
Reaction Steps
0.11 g(0.005 mol) of metallic sodium was dissolved in 30 g of dry phenol. To the resulting solution was added 0.93 g(0.005 mol) of 3-chloro-6-allylthiopyridazine and then the reaction solution was stirred for 3 hours at 160±5° C. After the reaction was allowed to stop, the reaction solution was cooled and adjusted to alkaline (pH 14) with 2N--NaOH, thereby precipitating the crystals. The precipitated crystal was extracted with diethyl ether and then treated according to the same manner as Example 1 to obtain the title compound as a crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05942511 |
|---|
| Source dataset | uspto-grants-1999_08 |
|---|
| ORD ID | ord-2571025325ce4872a997c0b9cbe25cda |
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| Source note | uspto-grants-1999_08 |
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