Benzyl Alcohol → HCID 9859939, compound

Participants

Reaction Conditions

Reaction Steps

0.11 g(0.005 mol) of metallic sodium was dissolved in 20 ml of dry benzylalcohol. To the resulting solution was added 0.93 g(0.005 mol) of 3-chloro-6-allylthiopyridazine and then the reaction solution was stirred for 2 hours at 80±5° C. To remove the excessive benzylalcohol and the insoluble material (NaCl), the reaction mixture was purified with silica gel column chromatography (eluent: n-hexane/ethyl acetate=40/1, v/v) to obtain the title compound as a needle crystal.

Provenance & Evidence