(2S,4S)-1-(benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid → HCID 18391503, compound

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Reaction Steps

Saponification of the cis dimethyl ester 13 (0.502 g, 1.56 mmol) gave 0.44 g (96%) of the desired cis dicarboxylate as colorless prisms: mp 175°-176° C; [α]26D +30° (c 1.10, CH3OH); Spectra were identical in all respects to those of the enantiomer N-(benzyloxycarbonyl)-cis-4-carboxy-L-proline. Anal. Calcd for C14H15NO6 ; C, 57.34; H, 5.16; N, 4.78. Found: C, 57.43; H, 5.18; C, 4.68.

Provenance & Evidence