Dichloromethane → HCID 178526434, compound

Participants

Reaction Conditions

Reaction Steps

6.3 g (0.063 mol) of KNO3 are added, in small portions and at 0° C., to 12.8 g of 1-(acetyl),4-chloro, 3-(2,2-difluorobenzo-1,3-dioxol-4-yl)pyrazole dissolved in 21 ml of H2SO4 (96%) and 140 ml of CH2Cl2. The reaction mixture is stirred for 3 h at 0° C. and then poured poured onto 300 cm3 of ice. The precipitate is recovered by filtration, washed with water and then heptane and dried. We obtain 8.05 g of 4-chloro-3-(2,2-difluoro-5-nitrobenzo-1,3-dioxol-4-yl)pyrazole melting at 180° C. (yield 63%).

Provenance & Evidence