HCID 178478181, compound → HCID 178478548, compound

HRID 1586363Notes

Reaction equation

HRID 1586363 reaction equation
[Cl:1][C:2]1[C:3]([C:7]2[CH:12]=[C:11]([Cl:13])[CH:10]=[C:9]([Cl:14])[CH:8]=2)=[N:4][NH:5][CH:6]=1>C(OCC)C>[ClH:1].[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[C:9]([Cl:14])[CH:10]=[C:11]([Cl:13])[CH:12]=2)=[N:4][NH:5][CH:6]=1.[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[C:9]([Cl:14])[CH:10]=[C:11]([Cl:13])[CH:12]=2)=[N:4][NH:5][CH:6]=1

Participants

3

Reactant 1

HCID 178478181HCID 178478181, compound

Product 1

HCID 178478548HCID 178478548, compoundYield 77.6%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

2 g (0.008 mol) of 4-chloro-3-(3,5-dichlorophenyl)pyrazole are dissolved, at room temperature and with stirring, in 200 ml of diethyl ether. Sparging with hydrochloric acid is then carried out until precipitation has ended. The white solid is filtered and rinsed with ether to give 1.1 g (yield 52%, melting point: 175° C.) of 4-chloro-3-(3,5-dichlorophenyl)pyrazole hemihydrochloride.

Workup

  1. customSparging with hydrochloric acid
  2. customis then carried out until precipitation
  3. filtrationThe white solid is filtered
  4. washrinsed with ether

Sources & evidence

ORD record
ord-08857daf80a943b09997e599523ac755
Source dataset
uspto-grants-1999_08
Patent number
US05945382

Reaction notes

Loading…