Bromine → 2-Bromo-1-(3,5-dichlorophenyl)ethan-1-one

HRID 1586364Notes

Reaction equation

HRID 1586364 reaction equation
[Br:1]Br.[Cl:3][C:4]1[CH:5]=[C:6]([C:11](=[O:13])[CH3:12])[CH:7]=[C:8]([Cl:10])[CH:9]=1>C(O)(=O)C>[Br:1][CH2:12][C:11]([C:6]1[CH:5]=[C:4]([Cl:3])[CH:9]=[C:8]([Cl:10])[CH:7]=1)=[O:13]

Participants

4

Reactant 2

HCID 24408BromineHCID 27580583',5'-Dichloroacetophenone

Product 1

HCID 126224902-Bromo-1-(3,5-dichlorophenyl)ethan-1-oneYield 81%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1.03 ml (0.02 mol) of bromine are added, at room temperature, to 3.77 g (0.019 mol) of (3,5-dichlorophenyl)ethanone in solution in 50 ml of acetic acid. After stirring for 12 hours, evaporation of the acetic acid leads to the production of a yellow precipitate: 2-bromo-1-(3,5-dichlorophenyl)-1-ethanone (yield 81%).

Workup

  1. customevaporation of the acetic acid leads to the production of a yellow precipitate

Sources & evidence

ORD record
ord-9c5c0a69b0df46589f9d68d8d456516a
Source dataset
uspto-grants-1999_08
Patent number
US05945382

Reaction notes

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