HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridineethanamine → 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 36
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridineethanamine | HCID 75919 | — |
| Reactant | 6-(2,6-Dichlorophenyl)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one | HCID 10736701 | — |
| Product | 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 36 | HCID 5327883 | — |
Reaction Steps
This compound was prepared by a procedure similar to that described in Example 33 starting with 0.165 g (0.47 mmol) of 6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one of Example 37 and 1.00 g (8.20 mmol) of 2-(2-aminoethyl)-pyridine yielding 0.082 g of pure product; mp 173-174° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05945422 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-23802d376afe4c21941d67863ff11a5d |
| Source note | uspto-grants-1999_08 |