Sulfuric Acid → Benzenamine, 2-[(1H-benzimidazol-2-ylthio)methyl]-

Participants

Reaction Steps

A mixture of 9.0 g (60 mMol) of 2-mercaptobenzimidazole and 4.9 g (40 mMol) of 2-aminobenzyl alcohol were heated at 84° C. in a mixture of 45 ml of glacial acetic acid and 12.0 g (120 mMol) of sulfuric acid. After two hours an additional 1 g (8 mMol) of 2-aminobenzyl alcohol and 1 g of sulfuric acid were added. After one hour the reaction mixture was cooled and poured into cold benzenamine hemihydrate.

Provenance & Evidence