Diethyl Ether → HCID 13754165, compound

HRID 1586476Notes

Reaction equation

Cl.Cl.[NH:3]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[N:5]=[C:4]1[S:12][CH2:13][C:14]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[CH:16][C:15]=1[NH2:22].C([O:25]CC)C>>[NH:3]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[N:5]=[C:4]1[S:12]([CH2:13][C:14]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[CH:16][C:15]=1[NH2:22])=[O:25]

Participants

Reactant 2

HCID 3283Diethyl Ether

HCID 13754150HCID 13754150, compound

Product 1

HCID 13754165HCID 13754165, compound

Procedure

The title compound was prepared by the method of Example 3 using 2.20 g of the free base of the title product of Example 19 instead of the title product of Example 2. Trituration with diethyl ether gave 900 mg of the title compound: m.p. 152-153° C. Anal. Calc'd. for C15H5N3O2S: C, 59.78; H, 5.02; N, 13.94; S, 10.64. Found: C, 59.01; H, 4.97; N, 13.65; S, 10.65.

Sources & evidence

ORD record: ord-7c442de09a01489b839e8db302d0caed
Source dataset: uspto-grants-1999_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05945425

Reaction notes

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