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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 158657Generated: October 29, 2026

4-Piperidinemethanol → 1-(5-Tert-butyl-isoxazol-3-yl)-3-(3-{7-[2-(4-hydroxymethyl-piperidin-1-yl)-ethoxy]-6-methoxy-quinazolin-4-yloxy}-phenyl)-urea

https://huagongshe.com/reaction/158657

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidinemethanolHCID 420771—
Reactant1-(5-Tert-butyl-isoxazol-3-yl)-3-{3-[7-(2-chloro-ethoxy)-6-methoxy-quinazolin-4-yloxy]-phenyl}-ureaHCID 66876530—
Product1-(5-Tert-butyl-isoxazol-3-yl)-3-(3-{7-[2-(4-hydroxymethyl-piperidin-1-yl)-ethoxy]-6-methoxy-quinazolin-4-yloxy}-phenyl)-ureaHCID 44243262—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-b6e73bba48db4b18bb0fa6978473137e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)