Thionyl Chloride → 2-Methoxy-6-methylbenzoyl chloride

HRID 1586578Notes

Reaction equation

HRID 1586578 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:4]=1[C:5](O)=[O:6].S(Cl)([Cl:15])=O>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:4]=1[C:5]([Cl:15])=[O:6]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 2731702-Methoxy-6-methylbenzoic acid

Product 1

HCID 128926752-Methoxy-6-methylbenzoyl chloride

Procedure

A mixture of 1A (1.7 g, 10.2 mmol) and thionyl chloride (2 ml) is heated under reflux for 1 hour. The mixture is concentrated and the resulting benzoylchloride is used without further purification.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 1 hour
  3. concentrationThe mixture is concentrated
  4. customthe resulting benzoylchloride is used without further purification

Sources & evidence

ORD record
ord-311ef13ac6d1480fa4b21895b5ca9296
Source dataset
uspto-grants-1999_08
Patent number
US05945567

Reaction notes

Loading…