HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylamide → HCID 21216831, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylamide | HCID 6579 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 12,13-Dihydro-6-methyl-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione | HCID 5482350 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 21216831 | HCID 21216831 | — |
Reaction Steps
500 mg (1.47 mmol) 6,7,12,13-tetrahydro-6-methyl-5,7-dioxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole in 50 ml acetonitrile are stirred for 4 days at 20° C. with 1.05 g (14.8 mmol) acrylamide and 0.1 ml DBU. The suspension is evaporated, stirred with 30 ml dichloromethane/methanol (95:5 v/v) and the undissolved crystals are filtered off. 12-(2-carbamoylethyl)-6,7,12,13-tetrahydro-6-methyl-5,7-dioxo-5H-indolo[2,3-a]pyrrolo-[3,4-c]carbazole is obtained in the form of yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05945440 |
| Source dataset | uspto-grants-1999_08 |
| ORD ID | ord-50d4df2f29aa4c07a4b8e45be07c61f3 |
| Source note | uspto-grants-1999_08 |