反应详情

In an analogous manner, but effecting lysis of the epoxide ring in the 3-(2,3-epoxy-n-propoxy)benzamide of Example 3, B, using aqueous solution, dimethylamine, morpholine, methanol, or ethyl mercaptan, the corresponding compounds of the invention--3-(2,3-dihydroxy-n-propoxy)benzamide, 3-(3-(N,N-dimethylamino)-2-hydroxy-n-propoxy)benzamide, 3-(3-morpholino-2-hydroxy-n-propoxy)benzamide, 3-(3-methoxy-2-hydroxy-n-propoxy)benzamide, and 3-(3-ethylthio-2-hydroxy-n-propoxy)benzamide--are prepared.