HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroacetate → HCID 354312, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroacetate | HCID 7751 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Hydroxybenzamide | HCID 342403 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 354312 | HCID 354312 | 72.5% |
Reaction Steps
The subject compound was prepared using the general method of Example 3, except that 10.0 g (72.9 mmol) of 3-hydroxybenzamide was reacted with 29.0 g (236.6 mmol) of ethyl chloroacetate and 19.0 g (137.5 mmole) of K2CO3 in the presence of 150 cc dry DMF. There was obtained 11.8 g (72%) of the desired product having an mp of 158°-159° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05215738 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-d4317d0437de49b5bd4544fc46142249 |
| Source note | uspto-grants-1993_06 |