Nicotinamide → HCID 22051612, compound

HRID 1586622Notes

Reaction equation

[C:1]([NH2:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[NH4+].[C:11]([NH:14]C1C=NC=C(C=1)C([O-])=O)(=[O:13])[CH3:12]>>[C:11]([NH:14][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([CH:7]=1)[C:1]([NH2:9])=[O:8])(=[O:13])[CH3:12]

Participants

Reactant 2

HCID 936Nicotinamide

HCID 131717951HCID 131717951, compound

Product 1

HCID 22051612HCID 22051612, compound

Procedure

The above salt is converted to the desired nicotinamide derivative by conversion to the methyl ester and then to the corresponding amide.

Sources & evidence

ORD record: ord-f8643b904ae14049b198295e014db344
Source dataset: uspto-grants-1993_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05215738

Reaction notes

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