Sulfuryl chloride → HCID 19758717, compound

Participants

Reaction Steps

Sulphuryl chloride (9.5 g, 70.2 m mol) in dichloromethane (15 ml) was slowly added to a solution of the 4-equivalent coupler from (d) (40 g, 70.2 m mol) in dichloromethane (250 ml). After stirring at room temperature for 20 h, the volatiles were evaporated under reduced pressure. The crude product was purified by silica gel column chromatography (elutant 10% ethyl acetate in petrol (b.p. 60°-80° C.)) followed by recrystallization from methanol to give a white solid (25.2 g, 60%).

Provenance & Evidence