HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1586649Generated: November 3, 2026
4-Hydroxymethylpyridine → HCID 14725098, compound
https://huagongshe.com/reaction/1586649
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Hydroxymethylpyridine | HCID 11472 | — |
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14725098 | HCID 14725098 | — |
Reaction Steps
20.3 g of p-nitrophenyl chloroformate were dissolved in 150 ml of CH2Cl2 (absolute) and the solution was cooled to 0° C. under N2. 520 mg of 4-dimethylaminopyridine (DMAP) were added and 10 g of 4-hydroxymethylpyridine in 50 ml of CH2Cl2 (absolute) were then added dropwise to this solution. The mixture was stirred overnight at R.T. and the crystals which had precipitated were filtered off. The crystals were recrystallized using fresh CH2Cl2 under the influence of heat and, after cooling, were filtered off again.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05215968 |
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| Source dataset | uspto-grants-1993_06 |
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| ORD ID | ord-7efb2ec7610e471d85e735766a4ff50a |
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| Source note | uspto-grants-1993_06 |
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